{"product_id":"new-product-229796","title":"CaMKIIα\/δ (phospho-T286) polyclonal antibody","description":"\u003cp\u003eThe Ca2+\/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine\/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine\/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated α, β, γ and δ, which may or may not be co-expressed in the same tissue type. CaMKIIα is autophosphorylated on Thr 286 upon the binding of the Ca2+\/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+\/CaM trapping, which is thought to be involved in the synaptic encoding of information.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662649671960,"sku":"BS4773","price":348.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_911ef230-ded4-4a7d-b3cb-7d661e02dd5a.jpg?v=1707491511","url":"https:\/\/danabiosci.com\/products\/new-product-229796","provider":"Dana Bioscience","version":"1.0","type":"link"}