{"product_id":"new-product-229311","title":"ACTR1A polyclonal antibody","description":"\u003cp\u003eThe dynactin complex is a macromolecular complex that consists of 10-11 distinct subunits. This complex is critical for the function of dynein, a molecular motor protein. Dynactin plays a role in ER to Golgi transport, spindle formation, chromosome movement, axon guidance, nuclear positioning and the centripetal movement of lysosomes and endosomes. Centractin is a subunit of the dynactin complex that exists in multiple isoforms. The α isoform, also known as actin-related protein 1 homolog A (Arp1) and previously referred to as centractin, is the most abundant isoform in the dynactin complex. The β isoform, also known as actin-related protein 1 homolog B, shares 90% identity with the α isoform. The two isoforms, α and β, are expressed at a ratio of 15:1 respectively. The backbone filament structure of the dynactin complex (important for the arrangement of other complex proteins) is composed of 9-11 subunits of α\/β-centractin.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662495138072,"sku":"BS6315","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_3f3b0f30-6cb4-4422-b9ae-d710bc2316af.jpg?v=1707489202","url":"https:\/\/danabiosci.com\/products\/new-product-229311","provider":"Dana Bioscience","version":"1.0","type":"link"}