{"product_id":"new-product-229308","title":"AGPAT2 polyclonal antibody","description":"\u003cp\u003ePhosphatidic acid and lysophosphatidic acid are phospholipids involved in lipid biosynthesis and signal transduction. LPAAT-β (lysophosphatidic acid acyltransferase, beta), also known as AGPAT2, BSCL, BSCL1, LPAAB or 1-AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2), is a multi-pass membrane protein localized to the endoplasmic reticulum that catalyzes the synthesis of phosphatidic acid from lysophosphatidic acid. Predominantly expressed in heart and liver, LPAAT-β belongs to the LPAAT family of proteins that have a well-known role in lipid biosynthesis. In addition, LPAAT family members may also play a role in tumor progression. Mutations in the gene encoding LPAAT-β can result in the autosomal recessive disorder CGL1 (congenital generalized lipodystrophy type 1). CGL1, also known as Berardinelli-Seip congenital lipodystrophy type 1 (BSCL1), is a disorder characterized by insulin resistance, early onset of diabetes, hepatic steatosis, scarcity of adipose tissue and hypertriglyceridemia.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":47662490911000,"sku":"BS6318","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_9c458346-1ab7-40f5-835a-50a89c3c0e39.jpg?v=1707489189","url":"https:\/\/danabiosci.com\/products\/new-product-229308","provider":"Dana Bioscience","version":"1.0","type":"link"}