{"product_id":"new-product-229215","title":"MNK2 (Phospho-T249) polyclonal antibody","description":"\u003cp\u003eThe MAPKAP kinases (for MAP kinase activated protein kinases) are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser\/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. These include the serine\/threonine kinases Rsk-1 (also designated MAPKAP kinase-1), Rsk-2 and Rsk-3, which are phosphorylated by ERK1 and ERK2. Similarly, p38 phosphorylates and activates the serine\/threonine kinases MAPKAP kinase-2 and MAPKAP kinase-3 (also designated 3pK). The serine\/ threonine kinases Mnk1 and Mnk2 are substrates for both ERK and p38 MAP kinases. Mnk2 exists as multiple isoforms, including Mnk2a and Mnk2b, due to alternative splicing events.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662470103320,"sku":"BS64558","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_0d94de7f-b9b0-4388-81d9-07f11ffb824c.jpg?v=1707488770","url":"https:\/\/danabiosci.com\/products\/new-product-229215","provider":"Dana Bioscience","version":"1.0","type":"link"}