{"product_id":"new-product-229141","title":"MDM2 (phospho Ser186\/S188) polyclonal antibody","description":"\u003cp\u003eMDM2 proto-oncogene(MDM2) Homo sapiens This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013],\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":47662450442520,"sku":"BS65101","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_ced26e10-df46-4777-b636-26ca29c6915c.jpg?v=1707488437","url":"https:\/\/danabiosci.com\/products\/new-product-229141","provider":"Dana Bioscience","version":"1.0","type":"link"}