{"product_id":"new-product-228909","title":"PER2\/Period circadian protein 2 Polyclonal Antibody","description":"\u003cp\u003ePER2, a mammalian homologue of the Drosophila period gene, shares a 40% homology with PER1 including the protein dimerization PAS domain. PER2 is a circadian regulator that may act as a transcription factor. It behaves as a negative element in circadian transcriptional loop. PER2 does not appear to bind DNA, suggesting indirect transcriptional inhibition. Expression oscillates with a 24 hour rhythm in the suprachiasmatic nucleus (SCN) and the whole eyes. Oscillations are maintained under constant darkness and are responsive to changes of the light\/dark cycles. There is a 4 hour time delay between PER1 and PER2 oscillations. The expression rhythms appear to originate from retina.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat,Dog,Cow,Horse,","offer_id":47662419673368,"sku":"BS65878","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_71df0602-7be7-44de-a78d-af03fca763db.jpg?v=1707487196","url":"https:\/\/danabiosci.com\/products\/new-product-228909","provider":"Dana Bioscience","version":"1.0","type":"link"}