{"product_id":"new-product-228832","title":"KIR2DL3 polyclonal antibody","description":"\u003cp\u003eNKAT (NK-associated transcripts) gene products, known as killer immuno-globulin-like receptors or KIRs, downregulate the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. This family of receptors is characterized by an extracellular region with two to three immunoglobulin-superfamily domains and a cytoplasmic domain with an antigen receptor activation motif (ARAM). KIRs and other inhibitory receptors also possess a common cytoplasmic sequence (I\/VxYxxL\/V) known as an ITIM (immunoreceptor tyrosine-based inhibitory motif). The human inhibitory human killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3), also referred to as CD158b, is an inhibitory receptor that is specific for the human MHC class I molecule HLA-Cw3 and related alleles.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":47662402371864,"sku":"BS6643","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_5ecc5129-02d1-4ce9-9ccd-73b252754bbf.jpg?v=1707486747","url":"https:\/\/danabiosci.com\/products\/new-product-228832","provider":"Dana Bioscience","version":"1.0","type":"link"}