{"product_id":"new-product-228664","title":"CD207 polyclonal antibody","description":"\u003cp\u003eLangerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immunostimulatory capacity and play a central role in the initiation and regulation of immune responses . Langerin (CD207) is a Ca(++)-dependent, C-type lectin domain-containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG) . BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T-cells. Human spleen, lymph node, thymus, liver, lung and heart express langerin protein. The human langerin gene maps to chromosome 2p13 and encodes a 328 amino acid protein .\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":47662387822872,"sku":"BS6881","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_f6298727-a989-4c6b-8583-636e7549bb6c.jpg?v=1707485845","url":"https:\/\/danabiosci.com\/products\/new-product-228664","provider":"Dana Bioscience","version":"1.0","type":"link"}