{"product_id":"new-product-228226","title":"CCL11 polyclonal antibody","description":"\u003cp\u003eEotaxin (also designated eotaxin-1) is a member of the C-C or β family of chemokines which is characterized by a pair of adjacent cysteine residues. Eotaxin was first purified from the bronchoalveolar lavage fluid of guinea pigs challenged with an aerosol allergen, and serves as a potent chemoattractant for eosinophils. Eosinophilia is a prominent feature of several allergic conditions and is thought to be a central event in maladies such as bronchial asthma, dermatitis, conjunctivitis and possibly inflammatory bowel disease. The cognate eotaxin receptor has been identified. Originally described as mouse orphan receptor (MIP-1a receptor-like 2), CKR-3 has been shown to not only serve as the high affinity receptor for eotaxin, but also for RANTES and MCP-3. CKR-3 is expressed on the cell surface of primary eosinophils and does not bind to other members of the C-C or C-X-C family of chemokines. CKR-3 also serves as a co-receptor for a restricted subset of viruses.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662320714008,"sku":"BS70816","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_645bc537-7496-4c7f-9cf0-2ef3dfd77950.jpg?v=1707483515","url":"https:\/\/danabiosci.com\/products\/new-product-228226","provider":"Dana Bioscience","version":"1.0","type":"link"}