{"product_id":"new-product-228141","title":"KDM5B polyclonal antibody","description":"\u003cp\u003eHistone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL\/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":47662299283736,"sku":"BS70906","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_1c85f0c5-ccc3-4c51-984a-28ef388f998d.jpg?v=1707483170","url":"https:\/\/danabiosci.com\/products\/new-product-228141","provider":"Dana Bioscience","version":"1.0","type":"link"}