{"product_id":"new-product-228094","title":"TGS1 polyclonal antibody","description":"\u003cp\u003eCatalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":47662280311064,"sku":"BS70955","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_fabd1eb3-514d-49c6-bdaf-1587cb34d071.jpg?v=1707482953","url":"https:\/\/danabiosci.com\/products\/new-product-228094","provider":"Dana Bioscience","version":"1.0","type":"link"}