{"product_id":"new-product-227920","title":"EpoR polyclonal antibody","description":"\u003cp\u003eThe erythropoietin receptor (EPOR) is a member of the cytokine receptor family. There are several isoforms including: EPOR-F (full length), EPOR-S (soluble form), and EPOR-T (truncated form). Upon erythropoietin (EPO) binding, the EPOR activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras\/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated EPOR appears to have a role in erythroid cell survival. Defects in the EPOR may produce erythroleukemia and familial erythrocytosis. A functional EPOR is found in the cardiovascular system, including endothelial cells and cardiomyocytes, and data suggest that the EPO\/EPO receptor system plays an important role in cardiac function. In animal studies, treatment with EPO during ischemia\/reperfusion in the heart has been shown to limit the infarct size and the extent of apoptosis.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662244036888,"sku":"BS7113","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_ee2c372a-d67e-4447-bf0f-00b94164db00.jpg?v=1707482050","url":"https:\/\/danabiosci.com\/products\/new-product-227920","provider":"Dana Bioscience","version":"1.0","type":"link"}