{"product_id":"new-product-227516","title":"ERH polyclonal antibody","description":"\u003cp\u003eERH (enhancer of rudimentary homolog), also known as DROER, is a 104 amino acid transcriptional coregulator that is ubiquitously expressed and highly conserved among eukaryotes. ERH may play a role in cell cycle regulation and pyrimidine biosynthesis. ERH represses the function of the coactivator PCBD, preventing it from enhancing the activity of the tissue-specific transcription factor HNF-1 (hepatocyte nuclear factor-1). HNF-1 is a homeodomain transcription factor that binds DNA as a dimer and the HNF-1\/DNA complex is stabilized by PCBD. By repressing PCBD, ERH disrupts the stability of the HNF-1\/DNA complex, affecting the expression of multiple genes in the liver. The structure of ERH is characterized by a single domain consisting of three α-helices and four β-strands.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":47662197473560,"sku":"BS71515","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_ee700953-3677-4d98-b6ed-006fa31853b5.jpg?v=1707479945","url":"https:\/\/danabiosci.com\/products\/new-product-227516","provider":"Dana Bioscience","version":"1.0","type":"link"}