{"product_id":"new-product-227167","title":"DEFB4 polyclonal antibody","description":"\u003cp\u003eβ-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Unlike the other previously described human β-defensins, human β-defensin 4 (hBD-4) expression is restricted to a few tissues, with highest expression in testis. A restricted pattern is also exhibited by mouse β-defensin 4. Rat β-defensin 4 (also desiganated BD-4, RBD-4, BD-2, and RBD-2) is developmentally regulated in the lung and is predominantly expressed in the lung and, to a lesser extent, in the trachea and tongue. It exhibits a regulation pattern similar to that of specific genes involved in host defense around the time of birth. The selectivity in both expression pattern and antimicrobial activity of human β-defensin 4 suggests that it is best suited to act at the epithelial locations where it is expressed.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662145667352,"sku":"BS7188","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_7f34ce03-0acd-4c91-b15d-9a45821fdb45.jpg?v=1707478223","url":"https:\/\/danabiosci.com\/products\/new-product-227167","provider":"Dana Bioscience","version":"1.0","type":"link"}