{"product_id":"new-product-226922","title":"DBNL polyclonal antibody","description":"\u003cp\u003eHIP-55 (HPK1-interacting protein of 55 kDa), also known as ABP1, SH3P7 or DBNL (drebrin-like), is a 430 amino acid cytoplasmic protein that belongs to the ABP1 family. HIP-55 binds to F-actin but is not involved in actin polymerization, capping or bundling. In addition to containing an ADF-H domain, HIP-55 also consists of a SH3 domain, which mediates interaction with SHANK2, SHANK3 and PRAM-1. HIP-55 acts as an actin-binding adapter protein and as a common effector of antigen receptor-signaling pathways in leukocytes. As a key component of the immunological synapse, HIP-55 regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. HIP-55 is degraded by caspases during apoptosis.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47662116241688,"sku":"BS72129","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_80d0c72d-bc04-4099-b93d-1454863fa548.jpg?v=1707477166","url":"https:\/\/danabiosci.com\/products\/new-product-226922","provider":"Dana Bioscience","version":"1.0","type":"link"}