{"product_id":"new-product-226774","title":"UHRF1 polyclonal antibody (ChIP Grade)","description":"\u003cp\u003eUHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5-CCAAT-3 box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1\/S transition and may be involved in DNA repair and chromosomal stability. UHRF1s ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":47662089797912,"sku":"BS7227","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_5ed6214e-c608-4db6-a27b-e76b5324ddda.jpg?v=1707476280","url":"https:\/\/danabiosci.com\/products\/new-product-226774","provider":"Dana Bioscience","version":"1.0","type":"link"}