{"product_id":"new-product-226558","title":"IBTK polyclonal antibody","description":"\u003cp\u003eBruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":47662020821272,"sku":"BS72498","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_0a2a225a-1c49-4dfe-bbc4-0a3a35bb6166.jpg?v=1707475159","url":"https:\/\/danabiosci.com\/products\/new-product-226558","provider":"Dana Bioscience","version":"1.0","type":"link"}