{"product_id":"new-product-226332","title":"HCAR2 polyclonal antibody","description":"\u003cp\u003eActs as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Rat","offer_id":47661964624152,"sku":"BS72723","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_ad9e87a6-8f92-4528-9744-c47762640d48.jpg?v=1707474018","url":"https:\/\/danabiosci.com\/products\/new-product-226332","provider":"Dana Bioscience","version":"1.0","type":"link"}