{"product_id":"new-product-225707","title":"BBOX1 polyclonal antibody","description":"\u003cp\u003eBBOX1 (butyrobetaine (γ), 2-oxoglutarate dioxygenase 1), also known as BBH, BBOX, G-BBH (γ-butyrobetaine hydroxylase) or γ-BBH, is a member of the γ-BBH\/TMLD family of proteins. Localizing to the cytoplasm and predominantly expressed in kidney, BBOX1 plays a role in the biosynthesis of amines, polyamines and carnitines. More specifically, BBOX1 catalyzes the hydroxylation of γ-butyrobetaine to L-carnitine, a reaction that requires iron and ascorbate as cofactors. This is the last of five steps comprising the L-carnitine biosynthesis pathway and it is important for the proper transport of activated fatty acids across the mitochondrial membrane. Coupled to this reaction, BBOX1 simultaneously catalyzes the oxidative decarboxylation of α-ketoglutarate to succinate.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":47661901054232,"sku":"BS7873","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_5bc32dc1-5156-4680-97ee-2fdc7851a25b.jpg?v=1707470693","url":"https:\/\/danabiosci.com\/products\/new-product-225707","provider":"Dana Bioscience","version":"1.0","type":"link"}