{"product_id":"new-product-225592","title":"APEH polyclonal antibody","description":"\u003cp\u003eAPEH (Acyl-peptide hydrolase), also known as APH, OPH or ACPH, is a 732 amino acid cytoplasmic protein that exists as a homotetramer and functions to catalyze the hydrolysis of N-terminal acetylated amino acids from small acetylated peptides. Once hydrolyzed from the target peptide, the acetyl amino acid is further processed by an aminoacylase to produce acetate and a free amino acid. The gene encoding human APEH maps to a region on chromosome 3 that is deleted in various types of cancers, including renal cell carcinoma and small cell lung carcinoma, suggesting that APEH may be involved in tumor transformation events. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47661892272408,"sku":"BS8085","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_e40c57c8-7d4a-4a0e-b705-d6680912eb2d.jpg?v=1707470114","url":"https:\/\/danabiosci.com\/products\/new-product-225592","provider":"Dana Bioscience","version":"1.0","type":"link"}