{"product_id":"new-product-225552","title":"ZMYND11 polyclonal antibody","description":"\u003cp\u003eThe adenovirus E1A gene products are nuclear phosphoproteins with the ability to transactivate other adenovirus genes. BS69 specifically interacts with adenovirus 5 E1A and inhibits transactivation by the 289R E1A protein. BS69 interacts with the co-repressor N-CoR through an essential MYND domain in the carboxy terminus of N-CoR. BS69 also inhibits the transcriptional activity of c-Myb. During oncogenesis, this BS69\/Myb regulatory circuit maybe be a target for disruption . Another ubiquitously expressed member of the Myb gene family, b-Myb, also interacts with BS69 and N-CoR to function as a transcriptional repressor. BRAM1, a splice variant of BS69, binds specifically to bone morphogenetic protein type IA receptor (BMPR-IA). BRAM1 localizes to the cytoplasm of mammalian cells, while BS69 localizes to the cell nucleus . Unlike BS69, BRAM1 is unable to repress transcription .\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47661882900760,"sku":"BS8134","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_a3be9713-9ec2-4b26-8c8f-61e4efc16acd.jpg?v=1707469872","url":"https:\/\/danabiosci.com\/products\/new-product-225552","provider":"Dana Bioscience","version":"1.0","type":"link"}