{"product_id":"new-product-225470","title":"ERAF polyclonal antibody","description":"\u003cp\u003eα-hemoglobin stabilizing protein (AHSP), also designated erythroid associated factor (ERAF), is an erythroid-specific protein that acts as a chaperone to prevent the aggregation of α-hemoglobin during normal erythroid cell development.It specifically protects free α-hemoglobin from precipitation in live cells and in solution. It forms a heterodimer with free α-hemoglobin, but not with β-hemoglobin or hemoglobin A (α2-β-2). AHSP localizes to the cytoplasm and is expressed in the blood and bone marrow. The AHSP protein is downregulated\u003cbr\u003e\nin transmissible spongiform encephalopathies (TSEs). AHSP may regulate pathological states of α-hemoglobin excess such as β-thalassemia,a group of hereditary disorders involving the decreased production of normal adult hemoglobin (HbA) that are characterized by a deficiency in the synthesis of β-globin chains.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47661858357528,"sku":"BS8238","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_f89a11af-df87-4e44-b100-e02eb7f8bb22.jpg?v=1707469398","url":"https:\/\/danabiosci.com\/products\/new-product-225470","provider":"Dana Bioscience","version":"1.0","type":"link"}