{"product_id":"new-product-225458","title":"IL17F polyclonal antibody","description":"\u003cp\u003eThe proinflammatory cytokine Interleukin 17 (IL-17) is produced by activated T cells to elicit potent cellular responses. IL-17 is secreted as a disulfide-linked homodimeric glycoprotein. A human IL-17 homolog IL-17E is a ligand for EV127\/IL-17BR, which is also known as IL-17 receptor homolog 1. IL-17E mRNA is detected at very low levels in several peripheral tissues. IL-17E induces the activation of NFκB and stimulates the production of the proinflammatory chemokine IL-8. In addition, IL-17E has catabolic activity on human articular cartilage. IL-17E is a unique pleiotropic cytokine that may be an important mediator of inflammatory and immune responses. Another homolog of IL-17, IL-17F, is a secreted cytokine expressed only in activated CD4+ T cells and activated monocytes. IL-17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and regulates cartilage matrix turnover.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse","offer_id":47661854687512,"sku":"BS8257","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_fb52d5e3-f887-4cda-b70e-745eebf8f6cf.jpg?v=1707469327","url":"https:\/\/danabiosci.com\/products\/new-product-225458","provider":"Dana Bioscience","version":"1.0","type":"link"}