{"product_id":"new-product-225335","title":"TMOD4 polyclonal antibody","description":"\u003cp\u003eOriginally isolated from human erythrocytes, the tropomodulin (TMOD) family of proteins cap the pointed end of actin filaments . A component of the membrane skeleton, TMOD binds to the amino terminus of tropomyosin, which coats the surface of actin, and thus blocks the elongation and depolymerization of actin filaments . Four TMOD isoforms, TMOD1 - TMOD4, have been characterized in humans. TMOD expression is isoform-specific; TMOD3 is expressed ubiquitously, whereas TMOD2 and TMOD4 are expressed in neuronal tissue and muscle, respectively. TMOD4, which has a similar organization to TMOD2, is intergenically spliced by the putative transformation suppressor gene product YL-1 . The human TMOD4 gene maps to the telomeric end of chromosome 1q12, and encodes a 351 amino acid protein . The expression and chromosomal location of the TMOD4 gene make it a candidate for limb girdle musclular dystrophy 1B.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47661816676632,"sku":"BS8427","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_7b198e84-4ba6-433b-87fd-20298e9479d3.jpg?v=1707468778","url":"https:\/\/danabiosci.com\/products\/new-product-225335","provider":"Dana Bioscience","version":"1.0","type":"link"}