{"product_id":"new-product-225032","title":"PARP3 polyclonal antibody","description":"\u003cp\u003ePoly(ADP-ribose) polymerase-3 (PARP-3) is part of the base excision repair (BER) pathway, catalyzing the poly(ADP-ribosyl)ation of nuclear proteins. Poly(ADP-ribosyl)ation, a post-translational modification following DNA damage, appears as an obligatory step in a detection\/signaling pathway leading to the reparation of DNA strand breaks. PARP-3 is a nuclear, DNA-binding protein, which interacts with PARP-1. PARP-3 is present in actively dividing tissues with highest levels in the kidney, skeletal muscle, liver, heart and spleen. Human PARP-3 maps to chromosome 3p21-3-p21.1, a gene region that undergoes alteration in solid malignant tumors.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":47661773062424,"sku":"BS8820","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_80b2f09c-3f97-4250-a5c0-08fdb62183f6.jpg?v=1707467215","url":"https:\/\/danabiosci.com\/products\/new-product-225032","provider":"Dana Bioscience","version":"1.0","type":"link"}