{"product_id":"new-product-225003","title":"GLK polyclonal antibody","description":"\u003cp\u003eSeveral mammalian kinases have been identified which exhibit sequence similarity to the Saccharomyces cerevisiae serine\/threonine kinase STE20. STE20 is involved in relaying signals from G-protein coupled receptors to cytosolic MAP kinase cascades, and it lies upstream of a MAP kinase kinase kinase. Mammalian STE20-like kinases include GLK, KHS, NIK, YSK1, HPK1, Krs-1, Krs-2 and human GC kinase. GLK (for GC-like kinase) is an 885 amino acid protein that shares a high degree of homology with GC kinase and HPK1. Like many of the STE20-like kinases, GLK specifically activates\u003cbr\u003e\nthe JNK pathway. Epistasis studies with dominant negative mutants of MEKK1 suggest that GLK functions upstream of MEKK1 in the JNK signaling pathway.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human,Mouse,Rat","offer_id":47661767688472,"sku":"BS8854","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_42d19f4c-ef0f-4e45-a340-50d5928dee39.jpg?v=1707467074","url":"https:\/\/danabiosci.com\/products\/new-product-225003","provider":"Dana Bioscience","version":"1.0","type":"link"}