{"product_id":"new-product-224803","title":"BIRC2 monoclonal antibody","description":"\u003cp\u003eThree mammalian homologs of baculovirus p35, designated MIHA (mammalian IAP homolog A), MIHB and MIHC have been described. These three mammalian inhibitor of apoptosis proteins (IAPs) are designated XIAP, c-IAP1 and c-IAP2, respectively. XIAP, c-IAP1 and c-IAP2 share an N-terminal baculovirus IAP repeat (BIR) motif and a C-terminal RING finger. Although c-IAP1 and c-IAP2 do not directly associate with the TNF receptor (TNF-R), they efficiently block TNF-mediated apoptosis through their interaction with the downstream TNF-R effectors, TRAF1 and TRAF2. The interaction between the TRAF1\/TRAF2 heterocomplexes and c-IAPs is dependent on a functional BIR motif.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Mouse \/ Human","offer_id":47661749076248,"sku":"MB0128","price":408.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_d0d85ef0-2951-4420-8551-8d2bbb3f1a3e.jpg?v=1707466127","url":"https:\/\/danabiosci.com\/products\/new-product-224803","provider":"Dana Bioscience","version":"1.0","type":"link"}