{"product_id":"new-product-224495","title":"Bcl-6 polyclonal antibody","description":"\u003cp\u003eBcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and Th1\/Th2 differentiation. Bcl-6 negatively regulates NFkB expression, thereby inhibiting NFkB-mediated cellular functions. HDAC- and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs). Bcl-6 is frequently deregulated in non-Hodgkin's B cell lymphomas. The human BCL6 gene has been shown to encode a protein of 706 amino acids.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human, Mouse","offer_id":47661712245016,"sku":"BS90130","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_fadc6bb0-1cf9-4b23-8d63-b666915f4bc5.jpg?v=1707464826","url":"https:\/\/danabiosci.com\/products\/new-product-224495","provider":"Dana Bioscience","version":"1.0","type":"link"}