{"product_id":"new-product-224489","title":"Bim polyclonal antibody","description":"\u003cp\u003ePro-apototic Bcl-2 family members promote cell death by neutralizing their anti-apoptotic relatives, which otherwise maintain cell viability by regulating caspase activity. Bim belongs to the BH3-only subgroup of Bcl-2 related proteins, and exists in three distinct isoforms, BimS (short), BimL (long) and BimEL (extra long). ERK1\/2 phosphorylates BimEL, resulting in rapid degradation of the isoform via the proteasome pathway. At least three sites for ERK1\/2 phosphorylation exist on BimEL, whereas ERK1\/2 does not effect BimS and BimL, implying a unique role for BimEL in cell survival signaling.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human","offer_id":47661711884568,"sku":"BS90137","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_87620c3e-4e0d-4973-8e61-108814da161e.jpg?v=1707464807","url":"https:\/\/danabiosci.com\/products\/new-product-224489","provider":"Dana Bioscience","version":"1.0","type":"link"}