{"product_id":"new-product-224472","title":"C\/EBP β polyclonal antibody","description":"\u003cp\u003eCCAAT-enhancer binding proteins (C\/EBP) are basic region\/leucine zipper (bZIP) transcription factors selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C\/EBP β is a member of the C\/EBP transcription factor family. The C\/EBP β gene encodes several isoforms containing truncated transcription activation domains due to the alternative translational initiation at multipe AUG start sites. C\/EBP β is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein (LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C\/EBP β contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C\/EBP β gene that has direct implication for acute phase response in liver cells.The C\/EBP β form requires phosphorylation for its DNA binding ability, and increase binding of C\/EBP β isoforms during acute-phase reaction occurs through its upregulation and structural modification.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human, Mouse, Rat","offer_id":47661709099288,"sku":"BS90153","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_2087c801-598b-44d8-af66-9d8ed04bd16f.jpg?v=1707464678","url":"https:\/\/danabiosci.com\/products\/new-product-224472","provider":"Dana Bioscience","version":"1.0","type":"link"}