{"product_id":"new-product-224276","title":"CXCR4 polyclonal antibody","description":"\u003cp\u003eThe C-X-C or a chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemo-attractant for T cells and monocytes but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB and CXCR-4 (also known as LESTR or fusin). CXCR-4 is highly homologous to the IL-8 receptors, sharing 37% sequence identity at the amino acid level. The IL-8 receptors bind to IL-8, NAP-2 and MSGA, while fusin binds to its cognate ligand, SDF-1. CXCR-4 has been identified as the major co-receptor for T-tropic HIV-1 and SDF-1 has been shown to inhibit HIV-1 infection.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human, Rat","offer_id":47661676855576,"sku":"BS90350","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_323337b4-9dff-4cd4-bca8-4f2b59c5b545.jpg?v=1707463830","url":"https:\/\/danabiosci.com\/products\/new-product-224276","provider":"Dana Bioscience","version":"1.0","type":"link"}