{"product_id":"new-product-224225","title":"DDIT3 polyclonal antibody","description":"\u003cp\u003eGADD 153 has been described as a growth arrest and DNA damage-inducible gene that encodes a C\/EBP-related nuclear protein. This protein has also been designated C\/EBP-homologous protein (CHOP-10). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C\/EBP proteins to direct GADD 153 dimers away from \"classical\" C\/EBP binding sites, recognizing instead unique \"nonclassical\" sites. Thus GADD 153 acts as a negative modulator of C\/EBP-like proteins in certain terminally differentiated cells, similar to the regulatory function of Id on the activity of Myo D and Myo D-related proteins involved in the development of muscle cells.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human, Mouse, Rat","offer_id":47661667090712,"sku":"BS90401","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_323d6408-def7-480b-a515-401029079e3c.jpg?v=1707463502","url":"https:\/\/danabiosci.com\/products\/new-product-224225","provider":"Dana Bioscience","version":"1.0","type":"link"}