{"product_id":"new-product-224013","title":"H-Cadherin polyclonal antibody","description":"\u003cp\u003eCadherins comprise a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogen-esis. Cadherins each contain a large extracellular domains characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin), also designated heart-cadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cell lines. Evidence suggests that decreased levels of T-cadherin indicate a progression in breast malignancies.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human, Mouse, Rat","offer_id":47661629145368,"sku":"BS90614","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_c5eca048-686e-4af2-a4b3-ada8e3c069ef.jpg?v=1707462387","url":"https:\/\/danabiosci.com\/products\/new-product-224013","provider":"Dana Bioscience","version":"1.0","type":"link"}