{"product_id":"new-product-223290","title":"TH polyclonal antibody","description":"\u003cp\u003eThe enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson’s disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10\/SWI6 motif-containing protein called V-1, and a variety of additional compounds.\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"100ul \/ Rabbit \/ Human, Mouse, Rat","offer_id":47661552927000,"sku":"BS91342","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BIOWORLD_a1f8bb5a-7235-41b3-b28b-a40fde4d531c.jpg?v=1707458708","url":"https:\/\/danabiosci.com\/products\/new-product-223290","provider":"Dana Bioscience","version":"1.0","type":"link"}