{"product_id":"new-product-145478","title":"KAL1 Polyclonal Antibody","description":"\u003cp\u003eKAL1 Polyclonal Antibody\u003c\/p\u003e\n\u003cp\u003eThe KAL1 polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of KAL1 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human KAL1 protein. The resulting polyclonal antibody is purified by affinity chromatography and validated for its specificity and sensitivity by various biochemical and immunological assays.\u003cbr\u003e\u003cbr\u003eThe KAL1 protein, also known as anosmin-1, is a secreted glycoprotein that plays a critical role in the development and function of the olfactory and gonadotropin-releasing hormone (GnRH) systems. Mutations in the KAL1 gene are associated with Kallmann syndrome, a rare genetic disorder characterized by hypogonadotropic hypogonadism and anosmia or hyposmia. Therefore, the detection and quantification of KAL1 protein expression are important for the diagnosis and treatment of Kallmann syndrome and related disorders.\u003cbr\u003e\u003cbr\u003eThe KAL1 polyclonal antibody has been extensively tested and validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and ELISA. This antibody recognizes a single band of the expected size (~100 kDa) in Western blot analysis of human and mouse brain lysates. In immunohistochemistry, this antibody shows specific staining of KAL1-positive cells in the olfactory bulb and GnRH neurons in the hypothalamus. In ELISA, this antibody exhibits a linear range of detection from 0.1 to 10 ng\/mL of recombinant KAL1 protein.\u003cbr\u003e\u003cbr\u003eIn summary, the KAL1 polyclonal antibody is a reliable and versatile tool for the detection and quantification of KAL1 protein expression in various biological samples. This antibody is suitable for use in basic research, clinical diagnosis, and drug development related to Kallmann syndrome and related disorders.\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL \/ 1 mg\/mL \/ Rabbit","offer_id":47632587981080,"sku":"E-AB-66792","price":420.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/E-AB-66792-IF01.jpg?v=1706918220","url":"https:\/\/danabiosci.com\/products\/new-product-145478","provider":"Dana Bioscience","version":"1.0","type":"link"}