{"product_id":"new-product-140671","title":"KEAP1 Polyclonal Antibody","description":"\u003cp\u003eKEAP1 Polyclonal Antibody\u003c\/p\u003e\n\u003cp\u003eThe KEAP1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of KEAP1 protein expression in various biological samples. This antibody is produced through a rigorous and meticulous process, ensuring its exceptional quality and performance.\u003cbr\u003e\u003cbr\u003eThe KEAP1 protein, also known as Kelch-like ECH-associated protein 1, plays a crucial role in the regulation of cellular responses to oxidative stress. It acts as a substrate adaptor protein for the Cullin 3-based E3 ubiquitin ligase complex, which targets the nuclear factor erythroid 2-related factor 2 (NRF2) for degradation. By doing so, KEAP1 maintains the balance of NRF2 levels, preventing excessive activation of antioxidant response elements (ARE) and maintaining cellular homeostasis.\u003cbr\u003e\u003cbr\u003eThe KEAP1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings. It exhibits minimal cross-reactivity with other proteins, ensuring accurate and reliable results. This antibody has been successfully used in Western blotting, immunohistochemistry, and immunofluorescence applications, enabling researchers to investigate KEAP1 expression and localization in different tissues and cell types.\u003cbr\u003e\u003cbr\u003eFurthermore, the KEAP1 Polyclonal Antibody demonstrates excellent performance in immunoprecipitation assays, facilitating the study of protein-protein interactions involving KEAP1. Its high affinity and specificity allow for efficient and precise isolation of KEAP1 complexes, enabling downstream analysis and characterization.\u003cbr\u003e\u003cbr\u003eIn summary, the KEAP1 Polyclonal Antibody is a valuable tool for researchers studying the KEAP1 protein and its involvement in cellular responses to oxidative stress. With its exceptional quality, specificity, and versatility, this antibody provides reliable and accurate results, contributing to the advancement of scientific knowledge in the field of oxidative stress and cellular homeostasis.\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL \/ 0.8 mg\/mL \/ Rabbit","offer_id":47628947095832,"sku":"E-AB-19309","price":420.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/E-AB-19309-WB01.png?v=1706946832","url":"https:\/\/danabiosci.com\/products\/new-product-140671","provider":"Dana Bioscience","version":"1.0","type":"link"}