{"product_id":"new-product-127138","title":"Recombinant Human LAG3\/CD223 Protein (His Tag)(Active)","description":"The Recombinant Human LAG3\/CD223 Protein (HIS TAG)(ACTIVE) is a highly purified and biologically active protein that is produced using recombinant DNA technology. This protein is a member of the immunoglobulin superfamily and is also known as Lymphocyte Activation Gene 3 (LAG3) or CD223. It is a transmembrane protein that is expressed on the surface of activated T cells, regulatory T cells, and natural killer cells.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe Recombinant Human LAG3\/CD223 Protein (HIS TAG)(ACTIVE) is produced in a mammalian expression system and is purified using a combination of chromatography techniques. The protein is then tagged with a histidine (HIS) tag to facilitate purification and detection. The protein is highly pure and has a molecular weight of approximately 70 kDa.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe Recombinant Human LAG3\/CD223 Protein (HIS TAG)(ACTIVE) is a potent immune checkpoint inhibitor that has been shown to enhance T cell activation and proliferation. It binds to MHC class II molecules on antigen-presenting cells and inhibits T cell activation by downregulating the T cell receptor signaling pathway. This protein has been extensively studied in preclinical models and has shown promising results in the treatment of various cancers.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe Recombinant Human LAG3\/CD223 Protein (HIS TAG)(ACTIVE) is supplied as a lyophilized powder and should be reconstituted in sterile water to a concentration of 0.1-1.0 mg\/ml. It should be stored at -20°C or below and should not be subjected to repeated freeze-thaw cycles. This protein is intended for research use only and should not be used for diagnostic or therapeutic purposes.","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":42685625270506,"sku":"PKSH033282","price":200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/elisa-1_8e0c9c10-f64f-4c2c-b386-ef911adda590.jpg?v=1706773442","url":"https:\/\/danabiosci.com\/products\/new-product-127138","provider":"Dana Bioscience","version":"1.0","type":"link"}