{"product_id":"new-product-117118","title":"Uncoated Human sRANKL(Soluble Receptor Activator of Nuclear factor-kB Ligand) ELISA Kit","description":"The Uncoated Human sRANKL ELISA Kit is a highly sensitive and specific assay designed for the quantitative measurement of soluble Receptor Activator of Nuclear factor-kB Ligand (sRANKL) in human serum, plasma, and cell culture supernatants. This kit is uncoated, meaning that the capture antibody is not pre-coated onto the microplate, allowing for greater flexibility in assay design and optimization. The kit includes all necessary reagents and components for the assay, including a pre-coated standard curve, detection antibody, and streptavidin-HRP conjugate.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe sRANKL protein is a key regulator of bone metabolism and is involved in the differentiation and activation of osteoclasts, the cells responsible for bone resorption. Dysregulation of sRANKL signaling has been implicated in a number of bone-related diseases, including osteoporosis, rheumatoid arthritis, and bone metastases. The Uncoated Human sRANKL ELISA Kit provides a reliable and accurate method for measuring sRANKL levels in biological samples, allowing for the identification of potential biomarkers and therapeutic targets for these diseases.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe assay is performed in a standard sandwich ELISA format, with the capture antibody and detection antibody binding to different epitopes on the sRANKL protein. The streptavidin-HRP conjugate then binds to the detection antibody, allowing for the detection of sRANKL levels through the addition of a chromogenic substrate. The kit has a detection range of 15.6-1000 pg\/mL, with a sensitivity of 7.8 pg\/mL. The Uncoated Human sRANKL ELISA Kit is a valuable tool for researchers and clinicians studying bone metabolism and related diseases, providing a reliable and accurate method for measuring sRANKL levels in biological samples.","brand":"Elabscience","offers":[{"title":"96T*5 \/ sRANKL","offer_id":47617559888152,"sku":"E-UNEL-H0190","price":399.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/Elabscience_logo_b83d026f-4807-485f-8074-425546a98865.png?v=1706716275","url":"https:\/\/danabiosci.com\/products\/new-product-117118","provider":"Dana Bioscience","version":"1.0","type":"link"}