{"product_id":"nalp4-rabbit-polyclonal-antibody-abcb09142","title":"NALP4 Rabbit Polyclonal Antibody","description":"\u003ch4\u003eAb type\u003c\/h4\u003e\u003cp\u003ePrimary antibody\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eNALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs| such as NALP4| have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD)| followed by a NACHT domain| a NACHT-associated domain (NAD)| and a C-terminal leucine-rich repeat (LRR) region. The long NALP| NALP1 (MIM 606636)| also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g.| CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al.| 2003 \u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman, Rat, Mouse\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eSynthesized peptide derived from human NALP4\u003c\/p\u003e\u003ch4\u003eStorage Stability\u003c\/h4\u003e\u003cp\u003e-20°C for 1 year\u003c\/p\u003e\u003ch4\u003eConcentration\u003c\/h4\u003e\u003cp\u003e1 mg\/ml\u003c\/p\u003e\u003ch4\u003eMolecularWeight_Da\u003c\/h4\u003e\u003cp\u003e109340\u003c\/p\u003e\u003ch4\u003esynonyms\u003c\/h4\u003e\u003cp\u003eNALP4\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42404657791210,"sku":"ABCB09142","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_30bff00c-93e8-42a5-8775-69cad3f34f44.png?v=1645226283","url":"https:\/\/danabiosci.com\/products\/nalp4-rabbit-polyclonal-antibody-abcb09142","provider":"Dana Bioscience","version":"1.0","type":"link"}