ABCbiolab
SKU:ABCB03655
Na+ CP type IV Alpha Polyclonal Antibody
Na+ CP type IV Alpha Polyclonal Antibody
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Ab type
Primary antibody
Background
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN4A (sodium voltage-gated channel alpha subunit 4) encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in SCN4A have been linked to several myotonia and periodic paralysis disorders.
Reactivity
Human;Mouse;Rat
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human SCN4A. AA range:431-480
Storage Stability
-20°C for one year
Concentration
1 mg/ml
MolecularWeight_Da
208032
synonyms
SCN4A; Sodium channel protein type 4 subunit alpha; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha