{"product_id":"n1215-100ug","title":"GBL Antibody","description":"\u003cp\u003eGBL (G protein beta subunit-like), also called MLST8 (MTOR associated protein, LST8 homolog), is a subunit of the mTOR signaling complexes mTORC1 and mTORC2, which help regulate cell growth and survival in response to growth factor (mTORC1 \u0026amp; 2) and nutrient (mTORC1) signaling. It is required for the phosphorylation of S6 kinase and the signal adaptor protein Insulin receptor substrate 1 and S473 phosphorylation of AKT. GBL is also a regulator of TNFa-induced NF-kB activity, with overexpression inhibiting and down-regulation enhancing NF-kB signaling (Kim et al, 2008).\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49477002985752,"sku":"N1215-100UG","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_f3e0163c-8800-406e-9b51-8546d990706f.jpg?v=1734486672","url":"https:\/\/danabiosci.com\/products\/n1215-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}