{"product_id":"n1084-25ug","title":"14-3-3 sigma Antibody","description":"\u003cp\u003e14-3-3 proteins are regulators of a diverse group of signaling proteins, including kinases, phosphatases, and transmembrane receptors, and have roles in a wide range of physiological processes including transcription, intracellular signaling, cell cycle control and apoptosis. There are seven 14-3-3 proteins in most mammals: beta, gamma epsilon, zeta, eta, sigma and tau. 14-3-3 sigma, also called Stratifin, is a product of the SFN gene. It is a tumor suppressor gene inactivated via DNA methylation. Reduced or no expression of 14-3-3 sigma is seen in various carcinoma including skin, breast and prostate, suggesting that 14-3-3 gene silencing may be involved in tumor progression.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"25 ug \/ Rabbit","offer_id":49477006524696,"sku":"N1084-25UG","price":219.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_696e9bb7-0b9d-4c41-8ac7-907a71109881.jpg?v=1734486940","url":"https:\/\/danabiosci.com\/products\/n1084-25ug","provider":"Dana Bioscience","version":"1.0","type":"link"}