{"product_id":"n1067-25ug","title":"SIN1 Antibody","description":"\u003cp\u003emTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86\/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"25 ug \/ Rabbit","offer_id":49477007048984,"sku":"N1067-25UG","price":219.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_23e4f9f1-f340-4824-ad61-04c4b68bc1cd.jpg?v=1734486980","url":"https:\/\/danabiosci.com\/products\/n1067-25ug","provider":"Dana Bioscience","version":"1.0","type":"link"}