{"product_id":"klf10-antibody-abccs44623","title":"KLF10 Antibody","description":"\u003ch4\u003eSize\u003c\/h4\u003e\u003cp\u003e100ul\u003c\/p\u003e\u003ch4\u003eClone Number\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eAliases\u003c\/h4\u003e\u003cp\u003eEarly growth response; alpha antibody; Early growth response; alpha like antibody; EGR A antibody; EGR alpha  antibody; EGR(A) antibody; EGR-alpha antibody; EGRA antibody; Egral antibody; EGRalpha antibody; Gdnfif antibody; KLF 10 antibody; KLF10 antibody; KLF10_HUMAN antibody; Krueppel like factor 10 antibody; Krueppel like factor10 antibody; Krueppel-like factor 10 antibody; Kruppel like factor 10 antibody; mGIF antibody; TGF-beta- inducible early gene antibody; TGFB inducible early growth response 1 antibody; TGFB inducible early growth response antibody; TGFB inducible early growth response protein 1 antibody; TGFB-inducible early growth response protein 1 antibody; TIEG 1 antibody; TIEG antibody; TIEG-1 antibody; TIEG1 antibody; Transforming growth factor beta inducible early growth response antibody; Transforming growth factor beta inducible early growth response protein 1 antibody; Transforming growth factor-beta-inducible early growth response protein 1 antibody; Zinc finger transcription factor TIEG antibody\u003c\/p\u003e\u003ch4\u003eImmunogen Species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eUniProt ID\u003c\/h4\u003e\u003cp\u003eQ13118\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eRecombinant Human Krueppel-like factor 10 protein (1-250AA)\u003c\/p\u003e\u003ch4\u003eRaised in\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eSpecies Reactivity\u003c\/h4\u003e\u003cp\u003eHuman\u003c\/p\u003e\u003ch4\u003eTested Applications\u003c\/h4\u003e\u003cp\u003eELISA\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eTranscriptional repressor which binds to the consensus sequence 5\\\\\\'-GGTGTG-3\\\\\\'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL\/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation.\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003ePurification Method\u003c\/h4\u003e\u003cp\u003eAntigen Affinity Purified\u003c\/p\u003e\u003ch4\u003eConjugate\u003c\/h4\u003e\u003cp\u003eNon-conjugated\u003c\/p\u003e\u003ch4\u003eBuffer\u003c\/h4\u003e\u003cp\u003ePBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eLiquid\u003c\/p\u003e\u003ch4\u003eStroage\u003c\/h4\u003e\u003cp\u003eUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003ch4\u003eTarget Names\u003c\/h4\u003e\u003cp\u003eKLF10\u003c\/p\u003e\u003ch4\u003eResearch Areas\u003c\/h4\u003e\u003cp\u003eEpigenetics and Nuclear Signaling; Cancer; Cardiovascular; Signal transduction\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"Default Title","offer_id":42359295148266,"sku":"ABCCS44623","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_3af6a27e-7de1-4fb8-a532-cac400d0167a.png?v=1650899568","url":"https:\/\/danabiosci.com\/products\/klf10-antibody-abccs44623","provider":"Dana Bioscience","version":"1.0","type":"link"}