{"product_id":"kdm2b-antibody-abccs56376","title":"KDM2B Antibody","description":"\u003ch4\u003eSize\u003c\/h4\u003e\u003cp\u003e100ug\u003c\/p\u003e\u003ch4\u003eClone Number\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eAliases\u003c\/h4\u003e\u003cp\u003e[Histone-H3]-lysine-36 demethylase 1B antibody; CXXC-type zinc finger protein 2 antibody; CXXC2 antibody; F box and leucine rich repeat protein 10 antibody; F box protein FBL10 antibody; F-box and leucine-rich repeat protein 10 antibody; F-box protein FBL10 antibody; F-box\/LRR-repeat protein 10 antibody; Fbl10 antibody; FBXL10 antibody; JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein antibody; JHDM1B antibody; JmjC domain-containing histone demethylation protein 1B antibody; Jumonji C domain containing histone demethylase 1B antibody; Jumonji domain-containing EMSY-interactor methyltransferase motif protein antibody; kdm2b antibody; KDM2B_HUMAN antibody; Lysine (K) specific demethylase 2B antibody; Lysine-specific demethylase 2B antibody; PCCX2 antibody; Protein containing CXXC domain 2 antibody; Protein JEMMA antibody; Protein-containing CXXC domain 2 antibody\u003c\/p\u003e\u003ch4\u003eImmunogen Species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eUniProt ID\u003c\/h4\u003e\u003cp\u003eQ8NHM5\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eRecombinant Human Lysine-specific demethylase 2B protein (1274-1336AA)\u003c\/p\u003e\u003ch4\u003eRaised in\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eSpecies Reactivity\u003c\/h4\u003e\u003cp\u003eHuman\u003c\/p\u003e\u003ch4\u003eTested Applications\u003c\/h4\u003e\u003cp\u003eELISA, IF; Recommended dilution: IF:1:50-1:200\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eHistone demethylase that demethylates \\'Lys-4\\' and \\'Lys-36\\' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 \\'Lys-4\\' and dimethylated H3 \\'Lys-36\\' residue while it has weak or no activity for mono- and tri-methylated H3 \\'Lys-36\\'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003ePurification Method\u003c\/h4\u003e\u003cp\u003e\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003ch4\u003eConjugate\u003c\/h4\u003e\u003cp\u003eNon-conjugated\u003c\/p\u003e\u003ch4\u003eBuffer\u003c\/h4\u003e\u003cp\u003ePreservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eLiquid\u003c\/p\u003e\u003ch4\u003eStroage\u003c\/h4\u003e\u003cp\u003eUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003ch4\u003eTarget Names\u003c\/h4\u003e\u003cp\u003eKDM2B\u003c\/p\u003e\u003ch4\u003eResearch Areas\u003c\/h4\u003e\u003cp\u003eEpigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"Default Title","offer_id":42288933732586,"sku":"ABCCS56376","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_4e29482c-91de-497e-a26a-dd41f61c9c89.png?v=1650883107","url":"https:\/\/danabiosci.com\/products\/kdm2b-antibody-abccs56376","provider":"Dana Bioscience","version":"1.0","type":"link"}