Skip to product information
1 of 1

ABCbiolab

SKU:ABCCS62788

KANK2 Antibody

KANK2 Antibody

Regular price $299.00 USD
Regular price Sale price $299.00 USD
Sale Sold out
Shipping calculated at checkout.

Size

100ug

Clone Number

Aliases

KANK2 antibody; ANKRD25 antibody; KIAA1518 antibody; MXRA3 antibody; SIP antibody; KN motif and ankyrin repeat domain-containing protein 2 antibody; Ankyrin repeat domain-containing protein 25 antibody; Matrix-remodeling-associated protein 3 antibody; SRC-1-interacting protein antibody; SIP antibody; SRC-interacting protein antibody; SRC1-interacting protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q63ZY3

Immunogen

Recombinant Human KN motif and ankyrin repeat domain-containing protein 2 protein (410-585AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

KANK2

Research Areas

Others

View full details