{"product_id":"il10rb-antibody-abccs57028","title":"IL10RB Antibody","description":"\u003ch4\u003eSize\u003c\/h4\u003e\u003cp\u003e100ug\u003c\/p\u003e\u003ch4\u003eClone Number\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eAliases\u003c\/h4\u003e\u003cp\u003eCd210 antibody; CDw210b antibody; CRF2 4 antibody; CRF2-4 antibody; CRFB4 antibody; Cytokine receptor class II antibody; Cytokine receptor class II CRF2 4 antibody; Cytokine receptor class-II member 4 antibody; Cytokine receptor family 2 member 4 antibody; Cytokine receptor family II member 4 antibody; D21S58 antibody; D21S66 antibody; I10R2_HUMAN antibody; IL-10 receptor subunit beta antibody; IL-10R subunit 2 antibody; IL-10R subunit beta antibody; IL-10R2 antibody; IL-10RB antibody; IL10R2 antibody; IL10RB antibody; Interleukin 10 receptor beta antibody; Interleukin-10 receptor subunit 2 antibody; Interleukin-10 receptor subunit beta antibody\u003c\/p\u003e\u003ch4\u003eImmunogen Species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eUniProt ID\u003c\/h4\u003e\u003cp\u003eQ08334\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eRecombinant Human Interleukin-10 receptor subunit beta protein (79-219AA)\u003c\/p\u003e\u003ch4\u003eRaised in\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eSpecies Reactivity\u003c\/h4\u003e\u003cp\u003eHuman, Rat\u003c\/p\u003e\u003ch4\u003eTested Applications\u003c\/h4\u003e\u003cp\u003eELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eShared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1\/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand\/receptor complex stimulate the activation of the JAK\/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003ePurification Method\u003c\/h4\u003e\u003cp\u003e\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003ch4\u003eConjugate\u003c\/h4\u003e\u003cp\u003eNon-conjugated\u003c\/p\u003e\u003ch4\u003eBuffer\u003c\/h4\u003e\u003cp\u003ePreservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eLiquid\u003c\/p\u003e\u003ch4\u003eStroage\u003c\/h4\u003e\u003cp\u003eUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003ch4\u003eTarget Names\u003c\/h4\u003e\u003cp\u003eIL10RB\u003c\/p\u003e\u003ch4\u003eResearch Areas\u003c\/h4\u003e\u003cp\u003eImmunology; Signal transduction\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"Default Title","offer_id":42285476413674,"sku":"ABCCS57028","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_2570bff8-d0de-4eb0-a3f4-8a80e726a0b0.png?v=1650884229","url":"https:\/\/danabiosci.com\/products\/il10rb-antibody-abccs57028","provider":"Dana Bioscience","version":"1.0","type":"link"}