{"product_id":"il-22-polyclonal-antibody-abcb02910","title":"IL-22 Polyclonal Antibody","description":"\u003ch4\u003eAb type\u003c\/h4\u003e\u003cp\u003ePrimary antibody\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eIL-10-related T cell-derived inducible factor (IL-22, also known as IL-TIF) is a cytokine that was originally identified in mouse as an IL-9 inducible gene in T cells and mast cells and shows 22% amino acid identity with IL-10. Additionally, IL-22 is induced by IL-9 in thymic lymphomas and by lectins in freshly isolated splenocytes. IL-22 is found in both the thymus and brain, which suggests that the role of this factor is not restricted to the immune system. IL-22 is a ligand for CRF2-4, a member of the class II cytokine receptor family. In contrast to IL-10, IL-22 does not inhibit the production of proinflammatory cytokines by monocytes in response to lipopolysaccharide nor does it impact IL-10 function on monocytes, but it has modest inhibitory effects on IL-4 production from Th2 T cells.\u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman;Mouse;Rat\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eThe antiserum was produced against synthesized peptide derived from the C-terminal region of human IL22. AA range:121-170\u003c\/p\u003e\u003ch4\u003eStorage Stability\u003c\/h4\u003e\u003cp\u003e-20°C for one year\u003c\/p\u003e\u003ch4\u003eConcentration\u003c\/h4\u003e\u003cp\u003e1 mg\/ml\u003c\/p\u003e\u003ch4\u003eMolecularWeight_Da\u003c\/h4\u003e\u003cp\u003e20011\u003c\/p\u003e\u003ch4\u003esynonyms\u003c\/h4\u003e\u003cp\u003eIL22; IL 22;; ILTIF; ZCYTO18; Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42404212834538,"sku":"ABCB02910","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_0be4c11c-63df-4f64-9113-cd0ac1a5b400.png?v=1645215977","url":"https:\/\/danabiosci.com\/products\/il-22-polyclonal-antibody-abcb02910","provider":"Dana Bioscience","version":"1.0","type":"link"}