{"product_id":"gfp-self-amplifying-rna-sarna-cr00021","title":"GFP Self-Amplifying RNA (saRNA), Unmodified – 8.5 kb Reporter RNA","description":"\u003cdiv style=\"max-width:900px;margin:0 auto;font-family:Arial,Helvetica,sans-serif;color:#1f2937;line-height:1.75;\"\u003e\n\n  \u003c!-- HERO --\u003e\n  \u003cdiv style=\"padding:34px;background:linear-gradient(135deg,#f0fdf4,#effaf7);border-radius:18px;margin-bottom:32px;\"\u003e\n\n    \u003cdiv style=\"font-size:13px;font-weight:700;color:#0f8a58;letter-spacing:.07em;\"\u003e\n      SELF-AMPLIFYING RNA · REPORTER RNA\n    \u003c\/div\u003e\n\n    \u003ch2 style=\"font-size:30px;line-height:1.3;margin:8px 0 12px;color:#111827;\"\u003e\n      GFP Reporter saRNA for Long-RNA Delivery \u0026amp; Expression Studies\n    \u003c\/h2\u003e\n\n    \u003cp style=\"font-size:18px;margin:0;\"\u003e\n      An \u003cstrong\u003e8,476 nt self-amplifying RNA\u003c\/strong\u003e encoding GFP,\n      designed as a reporter for saRNA delivery, transfection and\n      expression research.\n    \u003c\/p\u003e\n\n  \u003c\/div\u003e\n\n\n  \u003c!-- STOCK MESSAGE --\u003e\n  \u003cdiv style=\"display:flex;align-items:center;gap:12px;padding:16px 19px;background:#f0fdf4;border:1px solid #bbf0d1;border-radius:12px;margin:24px 0;\"\u003e\n\n    \u003cdiv style=\"width:10px;height:10px;border-radius:50%;background:#16a34a;flex:0 0 auto;\"\u003e\u003c\/div\u003e\n\n    \u003cdiv\u003e\n      \u003cstrong style=\"color:#166534;\"\u003eStocked by Dana Bioscience\u003c\/strong\u003e\n      \u003cdiv style=\"font-size:13px;color:#475467;\"\u003e\n        Available for U.S. research orders while inventory is in stock.\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n\n  \u003c\/div\u003e\n\n\n  \u003c!-- QUICK SPECS --\u003e\n  \u003cdiv style=\"display:grid;grid-template-columns:repeat(auto-fit,minmax(165px,1fr));gap:14px;margin:30px 0;\"\u003e\n\n    \u003cdiv style=\"padding:20px;background:#f8fafc;border-radius:14px;\"\u003e\n      \u003cdiv style=\"font-size:11px;color:#64748b;font-weight:700;\"\u003eRNA LENGTH\u003c\/div\u003e\n      \u003cstrong style=\"font-size:20px;\"\u003e8,476 nt\u003c\/strong\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"padding:20px;background:#f8fafc;border-radius:14px;\"\u003e\n      \u003cdiv style=\"font-size:11px;color:#64748b;font-weight:700;\"\u003eREPORTER\u003c\/div\u003e\n      \u003cstrong style=\"font-size:20px;\"\u003eGFP\u003c\/strong\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"padding:20px;background:#f8fafc;border-radius:14px;\"\u003e\n      \u003cdiv style=\"font-size:11px;color:#64748b;font-weight:700;\"\u003eCAP\u003c\/div\u003e\n      \u003cstrong style=\"font-size:20px;\"\u003eCap 1\u003c\/strong\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"padding:20px;background:#f8fafc;border-radius:14px;\"\u003e\n      \u003cdiv style=\"font-size:11px;color:#64748b;font-weight:700;\"\u003eFORMAT\u003c\/div\u003e\n      \u003cstrong style=\"font-size:20px;\"\u003e100 µg\u003c\/strong\u003e\n    \u003c\/div\u003e\n\n  \u003c\/div\u003e\n\n\n  \u003c!-- WHY --\u003e\n  \u003ch2 style=\"margin-top:50px;font-size:27px;color:#111827;\"\u003e\n    Why Use GFP saRNA?\n  \u003c\/h2\u003e\n\n  \u003cp\u003e\n    A GFP reporter makes it easy to visually evaluate whether a\n    self-amplifying RNA delivery system is successfully producing\n    protein inside cells.\n  \u003c\/p\u003e\n\n  \u003cp\u003e\n    Because this construct uses a self-amplifying RNA architecture,\n    it can be used as a practical model for evaluating saRNA\n    delivery and expression workflows before moving to a\n    therapeutic or experimental target sequence.\n  \u003c\/p\u003e\n\n  \u003cdiv style=\"display:grid;grid-template-columns:repeat(auto-fit,minmax(230px,1fr));gap:15px;margin:28px 0;\"\u003e\n\n    \u003cdiv style=\"padding:23px;border:1px solid #dbe5df;border-radius:14px;\"\u003e\n      \u003cstrong style=\"color:#0f8a58;\"\u003eDelivery Screening\u003c\/strong\u003e\n      \u003cp style=\"margin:7px 0 0;\"\u003e\n        Evaluate candidate transfection or RNA delivery conditions using a visible reporter.\n      \u003c\/p\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"padding:23px;border:1px solid #dbe5df;border-radius:14px;\"\u003e\n      \u003cstrong style=\"color:#0f8a58;\"\u003eLNP Development\u003c\/strong\u003e\n      \u003cp style=\"margin:7px 0 0;\"\u003e\n        Use GFP expression as a functional readout when comparing experimental delivery formulations.\n      \u003c\/p\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"padding:23px;border:1px solid #dbe5df;border-radius:14px;\"\u003e\n      \u003cstrong style=\"color:#0f8a58;\"\u003esaRNA Platform Research\u003c\/strong\u003e\n      \u003cp style=\"margin:7px 0 0;\"\u003e\n        Study expression from a long self-amplifying RNA construct in cell-based workflows.\n      \u003c\/p\u003e\n    \u003c\/div\u003e\n\n  \u003c\/div\u003e\n\n\n  \u003c!-- GFP READOUT --\u003e\n  \u003ch2 style=\"margin-top:50px;font-size:27px;color:#111827;\"\u003e\n    Simple Fluorescent Readout\n  \u003c\/h2\u003e\n\n  \u003cp\u003e\n    GFP provides a straightforward reporter signal that can be monitored\n    using common fluorescence-based research workflows.\n  \u003c\/p\u003e\n\n  \u003cdiv style=\"padding:28px;background:#0f172a;color:white;border-radius:17px;margin:26px 0;text-align:center;\"\u003e\n\n    \u003cdiv style=\"font-size:12px;color:#a7f3d0;font-weight:700;letter-spacing:.08em;\"\u003e\n      GFP FLUORESCENCE\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"font-size:27px;font-weight:700;margin-top:7px;\"\u003e\n      Ex \/ Em: 505 \/ 525 nm\n    \u003c\/div\u003e\n\n  \u003c\/div\u003e\n\n\n  \u003c!-- WORKFLOW --\u003e\n  \u003ch2 style=\"margin-top:52px;font-size:27px;color:#111827;\"\u003e\n    A Practical saRNA Evaluation Workflow\n  \u003c\/h2\u003e\n\n  \u003cdiv style=\"display:grid;grid-template-columns:repeat(auto-fit,minmax(180px,1fr));gap:12px;margin:27px 0;\"\u003e\n\n    \u003cdiv style=\"padding:20px;background:#f8fafc;border-radius:14px;text-align:center;\"\u003e\n      \u003cdiv style=\"font-size:12px;color:#0f8a58;font-weight:700;\"\u003eSTEP 1\u003c\/div\u003e\n      \u003cstrong\u003ePrepare Delivery System\u003c\/strong\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"padding:20px;background:#f8fafc;border-radius:14px;text-align:center;\"\u003e\n      \u003cdiv style=\"font-size:12px;color:#0f8a58;font-weight:700;\"\u003eSTEP 2\u003c\/div\u003e\n      \u003cstrong\u003eDeliver GFP saRNA\u003c\/strong\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"padding:20px;background:#f8fafc;border-radius:14px;text-align:center;\"\u003e\n      \u003cdiv style=\"font-size:12px;color:#0f8a58;font-weight:700;\"\u003eSTEP 3\u003c\/div\u003e\n      \u003cstrong\u003eMeasure GFP Expression\u003c\/strong\u003e\n    \u003c\/div\u003e\n\n    \u003cdiv style=\"padding:20px;background:#f8fafc;border-radius:14px;text-align:center;\"\u003e\n      \u003cdiv style=\"font-size:12px;color:#0f8a58;font-weight:700;\"\u003eSTEP 4\u003c\/div\u003e\n      \u003cstrong\u003eCompare Conditions\u003c\/strong\u003e\n    \u003c\/div\u003e\n\n  \u003c\/div\u003e\n\n\n  \u003c!-- PRODUCT SPECS --\u003e\n  \u003ch2 style=\"margin-top:52px;font-size:27px;color:#111827;\"\u003e\n    Product Specifications\n  \u003c\/h2\u003e\n\n  \u003cdiv style=\"overflow-x:auto;margin:25px 0;\"\u003e\n    \u003ctable style=\"width:100%;border-collapse:collapse;min-width:560px;\"\u003e\n\n      \u003ctbody\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;width:35%;\"\u003e\u003cstrong\u003eCatalog Number\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003eCR00021-100UG\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;\"\u003e\u003cstrong\u003eProduct\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003eGFP Self-Amplifying RNA \/ GFP saRNA (Unmodified)\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;\"\u003e\u003cstrong\u003ePackage\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003e100 µg\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;\"\u003e\u003cstrong\u003eRNA Length\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003e8,476 nt\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;\"\u003e\u003cstrong\u003eBase Composition\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003eUnmodified bases\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;\"\u003e\u003cstrong\u003eConcentration\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003e1.0 mg\/mL\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;\"\u003e\u003cstrong\u003e5' Cap\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003eCap 1\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;\"\u003e\u003cstrong\u003ePoly(A) Tail\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003eYes\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;\"\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003eLiquid\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;border-bottom:1px solid #e2e8f0;\"\u003e\u003cstrong\u003eBuffer\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;border-bottom:1px solid #e2e8f0;\"\u003e1 mM sodium citrate, pH 6.4\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n        \u003ctr\u003e\n          \u003ctd style=\"padding:14px;background:#f8fafc;\"\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n          \u003ctd style=\"padding:14px;\"\u003e−80°C or below; avoid repeated freeze\/thaw cycles\u003c\/td\u003e\n        \u003c\/tr\u003e\n\n      \u003c\/tbody\u003e\n\n    \u003c\/table\u003e\n  \u003c\/div\u003e\n\n\n  \u003c!-- COMPLEMENTARY QC --\u003e\n  \u003ch2 style=\"margin-top:52px;font-size:27px;color:#111827;\"\u003e\n    Working With Long saRNA?\n  \u003c\/h2\u003e\n\n  \u003cp\u003e\n    At 8,476 nt, CR00021 is also a useful example of why long-RNA\n    workflows may require higher-range RNA QC tools.\n  \u003c\/p\u003e\n\n  \u003cdiv style=\"display:grid;grid-template-columns:repeat(auto-fit,minmax(240px,1fr));gap:16px;margin:25px 0;\"\u003e\n\n    \u003ca href=\"\/products\/cr00005-50ul\" style=\"display:block;padding:24px;background:#f5f7ff;border:1px solid #cbd8ff;border-radius:15px;text-decoration:none;color:inherit;\"\u003e\n\n      \u003cdiv style=\"font-size:11px;font-weight:700;color:#155eef;\"\u003e\n        SIZE \u0026amp; INTEGRITY\n      \u003c\/div\u003e\n\n      \u003ch3 style=\"font-size:20px;margin:6px 0;\"\u003e12K High Range RNA Ladder\u003c\/h3\u003e\n\n      \u003cp style=\"margin:0;\"\u003e\n        200 nt–12 kb reference range suitable for comparison with long RNA constructs.\n      \u003c\/p\u003e\n\n      \u003cdiv style=\"margin-top:12px;color:#155eef;font-weight:700;\"\u003e\n        View CR00005 →\n      \u003c\/div\u003e\n\n    \u003c\/a\u003e\n\n\n    \u003ca href=\"\/search?q=C13005-K01\" style=\"display:block;padding:24px;background:#f1faf7;border:1px solid #bce0da;border-radius:15px;text-decoration:none;color:inherit;\"\u003e\n\n      \u003cdiv style=\"font-size:11px;font-weight:700;color:#087c75;\"\u003e\n        dsRNA IMPURITY\n      \u003c\/div\u003e\n\n      \u003ch3 style=\"font-size:20px;margin:6px 0;\"\u003eJ2-Based dsRNA ELISA\u003c\/h3\u003e\n\n      \u003cp style=\"margin:0;\"\u003e\n        Quantitative residual dsRNA analysis for IVT RNA research workflows.\n      \u003c\/p\u003e\n\n      \u003cdiv style=\"margin-top:12px;color:#087c75;font-weight:700;\"\u003e\n        View C13005 →\n      \u003c\/div\u003e\n\n    \u003c\/a\u003e\n\n  \u003c\/div\u003e\n\n\n  \u003c!-- FINAL CTA --\u003e\n  \u003cdiv style=\"margin-top:50px;padding:36px;background:linear-gradient(135deg,#064e3b,#0f8a58);color:white;border-radius:20px;\"\u003e\n\n    \u003cdiv style=\"font-size:13px;font-weight:700;color:#bbf7d0;\"\u003e\n      DANA BIOSCIENCE · saRNA RESEARCH\n    \u003c\/div\u003e\n\n    \u003ch2 style=\"font-size:28px;color:white;margin:9px 0 12px;\"\u003e\n      Start With a GFP Reporter saRNA\n    \u003c\/h2\u003e\n\n    \u003cp style=\"color:white;\"\u003e\n      Use CR00021 to evaluate saRNA delivery and expression\n      before moving to your target RNA construct.\n    \u003c\/p\u003e\n\n    \u003cp style=\"color:#dcfce7;font-size:13px;margin-bottom:0;\"\u003e\n      U.S. stock available while inventory lasts.\n    \u003c\/p\u003e\n\n  \u003c\/div\u003e\n\n  \u003cp style=\"margin-top:28px;font-size:13px;color:#738096;\"\u003e\n    For Research Use Only. Not for diagnostic or therapeutic use.\n    Expression performance may vary depending on cell type, delivery method,\n    formulation and experimental conditions.\n  \u003c\/p\u003e\n\n\u003c\/div\u003e","brand":"Croyezbio","offers":[{"title":"100 ug","offer_id":51525782634776,"sku":"CR00021-100UG","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/114326216_ba78f356-13f8-4e9e-b48c-6e60d692159d.png?v=1767835288","url":"https:\/\/danabiosci.com\/products\/gfp-self-amplifying-rna-sarna-cr00021","provider":"Dana Bioscience","version":"1.0","type":"link"}