{"product_id":"fy-ig0538-50","title":"β-Catenin Rabbit Polyclonal Antibody","description":"\u003cstrong\u003eCondition:\u003c\/strong\u003e 1mg\/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.\u003cbr\u003e\u003cstrong\u003eStore at:\u003c\/strong\u003e Store at -20°C. Stable for one year from the date of shipment.\u003cbr\u003e\u003cstrong\u003eRecommended dilutions:\u003c\/strong\u003e WB 1:1,000  IHC 1:500-1,000\u003cbr\u003e\u003cstrong\u003eSpecificity:\u003c\/strong\u003e Antibody can detect endogenous B-Catenin proteins.\u003cbr\u003e\u003cstrong\u003eAlternative Names:\u003c\/strong\u003e beta catenin,b-catenin,CTNB1,CTNNB1,FLJ25606,OTTHUMP00000162082\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e The distinct peripheral cytosolic proteins,alpha,beta and gamma catenin (102,94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.\u003cbr\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e WB,IHC\u003cbr\u003e\u003cstrong\u003eSpecies Cross-Reactivity:\u003c\/strong\u003e H,M,R\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 92KD\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eProtein MW    （KDa）:\u003c\/strong\u003e 92KD\u003cbr\u003e\u003cstrong\u003eSWISS:\u003c\/strong\u003e P35222\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eAntigen:\u003c\/strong\u003e Recombinant Protein\u003cbr\u003e\u003cstrong\u003eCategory:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eCatalog Number:\u003c\/strong\u003e FY-IG0538\u003cbr\u003e\u003cstrong\u003eTitle:\u003c\/strong\u003e β-Catenin Rabbit Polyclonal Antibody\u003cbr\u003e\u003cstrong\u003eSize List:\u003c\/strong\u003e ['50', '100']","brand":"Feiyuebio","offers":[{"title":"50","offer_id":50359094018328,"sku":"FY-IG0538-50","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/Feiyuebio_b8a46e75-de00-4e54-90f4-84ee9a801137.png?v=1749884758","url":"https:\/\/danabiosci.com\/products\/fy-ig0538-50","provider":"Dana Bioscience","version":"1.0","type":"link"}